kpmle2
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A 68-year-old man has stable mild exertional angina. He underwent coronary artery bypass graft surgery 2 years ago. His heart rate is 60/min, blood pressure is 120/60mm Hg, and left ventricular function and hemoglobin are normal. He takes maximally tolerated doses of nitrates and β-blockers.
Which of the following medications would decrease the likelihood of a cardiovascular event in this patient?
A. Angiotensin-converting enzyme inhibitors
B. Angiotensin receptor blockers
C. Digoxin
D. Dihydropyridine calcium blockers
E. Calcium channel blockers
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| Aashi
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A. Angiotensin-converting enzyme inhibitors
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| Vietnamese
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A
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| tamerbashir
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A
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| RX 135
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y not B...BOTH ARE SAME
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| drduck
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A
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| drduck
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still lot of difference...
start always with ACE inhibitors,
if patient uncomfortable....or any history of angioedema...or associated COPD.
u start with recptor blockrs like....the only drug in its class called LOSARTAN
it is seen that smokers donot tolerate ACEI well
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| cool doctor
Forum Junior
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why its A, he has normal LVF
anyway B,C,D,E r not indicated
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| cool doctor
Forum Junior
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Just found that Amlodipine has an indication for chronic stable angina so it could be D
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| Ivonne
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A
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| kpmle2
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The correct answer is A
Understand the pharmacologic treatment of chronic coronary artery disease.
Angiotensin-converting enzyme inhibitors reduce the incidence of cardiac events in patients who have coronary artery disease, independent of their effects on blood pressure and left ventricular function. Angiotensin receptor blockers do not have these effects and do not relieve the symptoms of angina, except indirectly, by reducing blood pressure. Digoxin does not relieve angina unless angina is being aggravated by rapid atrial fibrillation. Digoxin does not reduce the incidence of cardiac events or prolong life. Calcium channel blockers are excellent antianginal agents, although they do not reduce the incidence of cardiac events or prolong life.
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