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Kaplan Qbank USMLE



Author2 Posts
  #1

diffrentiating features -(define n biochemical featores n pathological as well :| )

1.osteopetrosis

2.osteoporosis

3.osteopenia

4.cells-osteoblast/osteoclast/osteocyte

5.renal osteodystrophy/pagets

  #2

osteopetrosis :arrow: thick sclerotic bones due to dec osteoclastic activity,bones are brittle,and fracture easily.
osteoporosis :arrow: osteopenia resulting in thin,fragile bones,easily susceptible to fractures,normal serum Ca,PO4 and alkaline phosphatase,X-ray shows generalized radiolucency of bone.
osteopenia :arrow: dec amount of normal bone formation
paget disease :arrow: excessive osteoclastic activity followed by disorganized osteoblastic activity,leading to mosaic pattern of thick but weak bones.labs show elevated serum alkaline phosphatase and urinary hydroxyproline levels.







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