crista
Forum Guru
Topics: 121
Posts: 408
|
A pt. with mildly compromised renal function is to be given a course of an aminoglycoside drug. In order to calculate the max. dose of the drug that can be given, which of the following measurements would be most helpful?
A) BUN and creatinine
B) Liver function tests
C) Wt. of the patient
D) Peak and trough drug levels
E) Body surface area of the patient
the answer is D and i don;t know why :oops:
|
| asmi
Forum Hero
Topics: 1043
Posts: 4,609
|
the peak and troughs are nothing but the plasma level changes/oscillations ...seen with intermittent dosing
Loading dose = Vd x Cs (where Cs is the desired plasma conc. of the drug)
|
| peekay
Forum Guru
Topics: 102
Posts: 588
|
my first guess was BUN and CREATININE LEVELS
than i realized peak and trough level is better.i was thinking if kidney fxn is compromised it will show as rise in BUN and CREAT levels.so i need to monitor peak and trough levels so that kidney fxn is not compromised.i hope i am correct
very tricky qs indeed.
|
| bright_nnn
Forum Senior
Topics: 17
Posts: 97
|
you r right it is a very tricky question.I belive it couldbe BUN and Creatinine.I mean u check the renal function By these tech. But to FIND THE MAX> dose it has to be the peak and Trough levels or the Oscillations in Plasma of Aminoglycoside.
How do we calculate the max. dose to be given?? :cry:
|
|
| |
| | | | |
