jean robert
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A neonate was born prematurely after 28 weeks gestation to a 22 y.o. primigravida.The baby was initially stable but then became severely hypoxemic and developed severe seizure activity. Eight months later,the infant is diagnosed with an obstructive hydrocephalus.This clinical picture resulted from which of the following conditions?
a) Germinal matrix hemorrhage
b) Down syndrome
c) Kernicterus
d) Congenital CMV infection
e) Medulloblatoma
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| Tiff
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A?
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| GOGETA
I'm Dr. GOGETA
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Why C is not the correct answer? or is it
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| angel23
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e)medulloblastoma
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| arlete
Intern in 2009!!!!!
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A
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| new_n_lost
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By Exclusion i am left with A
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| GOGETA
I'm Dr. GOGETA
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C is a very important basic concept
I'm not saying is the correct answer
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As a general rule, the better it felt when you said it, the more trouble it's going to get you into.
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| jean robert
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Correct answer A
Germinal matrix hemorrhage is the most common cause for intraventricular hemorrhage in premature infants. The germinal matrix , composed of highly vascularized tissue with primitive cells is most prominent between 22 and 30 weeks gestation.
Hemorrhages within this area readily occur with common neonatal problems such as
1.-Hypoxemia
2.-Hypercarbia
3.-Acidosis
4.-Changes in blood pressure.
Hemorrahges in germinal matrix can extend into the cerebral ventricles and from the there into the subarachnoid space.. Smaller hemorrhages can resolve without sequelae. With larger hemorrhages, organization of the blood in aqueduct of Sylvius or the fourth ventricle or foramina of Luschka may obstruct the flow of CSF, thus producing hydrocephalus.
The bilirubin staining of kernicterus doesn t result in scarring.
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