Tiff
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A 43 year old man with end stage renal disiase and a history of heart murmur and recurrent osteomyelitis is taken to the ER because of fever and confusion. He's been receiving hemodialysis for many years. An EKG shows vegetation on te aortic valve. Before the results of laboratory studies are available, initiation of epiric therapy with which of the following drugs would most likely be beneficial?
A. Chloramphemicol plus tetracycline
B Nafcillin plus erythrocmycin
C. Penicillin G plus tetracyle
D. Trimethoprim plus sulfamethoxazole
E. Vancomycin plus gentamicin
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| arlete
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E
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| Tiff
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E is correct! 
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| SILVER
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do you have explanations for the answers? plz post them.
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| Tiff
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In the case described, empiric therapy should cover infections due to Staphylococcus aureus and gram-negative bacteria. Vancomycin plus gentamicin is an example of a combination that is effective against these organisms.
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