shirini2
Forum Senior
Topics: 27
Posts: 86
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During a clinical trial, the difference in the success rates of two drugs was not statistically significant. This means that
1) there is no difference in drug effectiveness.
2) the demonstrated difference in the drugs' effectiveness could be due to chance alone.
3) the demonstrated difference in the drugs' effectiveness is too small to be clinically meaningful.
4) the two samples of patients on which the drugs were tested came from the same population.
5) the samples were not drawn in a statistically valid manner.
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| arlete
Intern in 2009!!!!!
Topics: 30
Posts: 2,212
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3
___________________
When men make the rules, God decides the exceptions.
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| shirini2
Forum Senior
Topics: 27
Posts: 86
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agree
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| cool doctor
Forum Junior
Topics: 1
Posts: 219
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| shirini2
Forum Senior
Topics: 27
Posts: 86
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Dear Friends. Found the answer of this Q. It's (2).
found exactly same Q except 2nd choice is: "there is a sizable probability that the demonstrated difference in the drugs' effectiveness is too small to be clinically meaningful." Which is same as here.
Unfortunately does not have any explanation. Just say's answer is (2).
I think 3 is incorrect because it's possible that the 2 drugs do have clinically meaningful differences but the sample size is too small to demonstrate this.
Do you agree?
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| plastic_surgery
Forum Junior
Topics: 2
Posts: 135
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In a study when the difference in effect is not statistically significant, always the choice 2 is correct based on null hypothesis.. Other possible correct answers esp. 1 and 3 depend on the condition of the study.. as Shirini mentioned the smaller sample size may make any difference, clinically relevant or not, insignificant. At the same time a very large sample may make a small but clinically irrelevant difference significant.
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| romano
Forum Newbie
Topics: 3
Posts: 18
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2.
Number 3 is there to trick you. A new drug doesn't have to be better than currently used ones to be clinically meningful. For example, the new drug can be just as good, but maybe it is cheaper, has less side effects etc. Then it is still useful clinically.
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