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Kaplan Qbank USMLE



Author13 Posts
  #1

A 12-year-old boy has had multiple episodes of ear pain accompanied by fever. On examination his right tympanic membrane is red and bulging. Laboratory studies show culture positive for Hemophilus influenzae. A year later he has conductive hearing loss on the right, and a head CT scan shows a mass in the right middle ear. Which of the following materials is most likely to be seen in the tissue curetted from his middle ear?

A Lipofuscin

B Russell bodies

C Neutrophils

D Cholesterol crystals

E Anthracotic pigment



  #2

C. Neutrophils??

Edited by drgho on 12/23/07 - 06:30 PM

  #3

C Neutrophils

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  #4

silver wrote:
C Neutrophils


Neutrophiles is something we see ACUTELY..this mass is discovered a year later by a CT scan which signifies a chronic process..

That mass is know as Cholesteotoma------>Complication of Otitis media------>Cholestrol crystals ------->D

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  #5

yes the answer is D

  #6

Aashi wrote:




That mass is know as Cholesteotoma------>Complication of Otitis media------>Cholestrol crystals ------->D


right! got the flashback from med. school as soon as you mentioned cholesteatoma. thanks for correcting mesmiling face


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  #7

Aashi wrote:


Neutrophiles is something we see ACUTELY..this mass is discovered a year later by a CT scan which signifies a chronic process..

That mass is know as Cholesteotoma------>Complication of Otitis media------>Cholestrol crystals ------->D

ok this is new for me because i thought a Cholesteotoma which is an ingrowth of the squamous epithelium which is keratinizined and its name is actually a misnomer because the entity does not contain cholesterol at all if any thing it does include granulation tissue. Please recheck the answer as i can assure you this is does have cholesterol crystals.

This is probably a Kaplan question I have also seen some mistakes in them.


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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #8

From here

A cholesteatoma consists of an accumulation of desquamated keratin epithelium in the middle ear cleft or any other pneumatized portion of the temporal bone. The envelope of a cholesteatoma is termed a matrix, and desquamated keratin is shed continually by the matrix and forms the central mass of the cholesteatoma, similar to the layers of an onion. The term cholesteatoma is a misnomer, since the entity does not contain cholesterol.


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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #9

"A cholesteatoma cyst consists of desquamating (peeling) layers of scaly or keratinised (horny) layers of epithelium, which may also contain cholesterol crystals"

"A history of ear infection or flooding of the ear during swimming should be taken seriously and investigated as cholesteatoma should be considered a possible outcome."

http://en.wikipedia.org/wiki/Cholesteatoma




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  #10

(D) CORRECT. The lipid from the red cell membranes is broken down and cholesterol crystals form. The boy has the complication of otitis media known as a cholesteatoma

  #11

Well, same as NNL I also thought that cholesteatoma is misnomer. Amazing is when you skim trough professional ORL weblinks, all state the name of this condition as a misnomer. Like this one too... http://www.otohns.net/default.asp?id=14061

Seems like only Wiki , is leaning towards he theory of cholesterol crystals....

And the many of forum members too... grin

Oh, I still agree , the boy suffers with cholesteatoma.


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  #12

angel23 wrote:
(D) CORRECT. The lipid from the red cell membranes is broken down and cholesterol crystals form. The boy has the complication of otitis media known as a cholesteatoma

Acquired cholesteatoma is usually diagnosed in older children and adults and with a previous history of middle ear disease. The cholesteatoma is most often found in the posterosuperior quadrant of the tympanic membrane with the associated presence of tympanic membrane retraction and/or perforation. Hearing loss is typically manifest with more extensive disease. Acquired cholesteatoma may be further subdivided into primary or secondary. Primary acquired cholesteatoma arises in the clinical setting of accumulation of squamous debris in a pre-existing retraction pocket. Secondary acquired cholesteatoma is most often accompanied by a perforation of the tympanic membrane with subsequent migration of squamous epithelium into the middle ear.
From here So there is no way that the explanation provided makes any sense.

Same goes for that question which says Coagulation necrosis in brain when we all know that its liquefactive. Looking into all the histological explanations given in different University sites and journals and articles one can conclude that Cholesteatoma is not due to the red cell defragmentation or the presence of lipids.


___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #13

this ques was 4rm webpath----cell injury







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