doc499 wrote:
is it D coz of abnormality of g caroxylation 
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| new_n_lost
Politically InCorrect
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The correct answer is D.
Deficiency of vitamin K produces a clotting disorder characterized by an elevated prothrombin time and easy bleeding, particularly in neonates (hemorrhagic disease of the newborn). The biochemical basis for this hemorrhagic tendency is that glutamate residues on Factors II (Thrombin), VII, IX, and X must be converted to gamma-carboxyglutamate residues (in a vitamin K-requiring reaction) for optimal activity.
The conversion of homocysteine to methionine (choice A) requires vitamin B12.
Conversion of methylmalonyl CoA to succinyl CoA (choice B) requires vitamin B12.
Degradation of cystathionine (choice C) requires vitamin B6.
Hydroxylation of proline (choice E) requires vitamin C. Vitamin C deficiency can cause easy bruising, but will not prolong the prothrombin time.
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| aml
Forum Senior
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D
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