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Kaplan Qbank USMLE



Author5 Posts
  #1

Which enzyme is an allosteric regulator of another enzyme on the list?

a.-Acetyl CoA carboxylase
b.-Pancreatic lipase
c.-Carnitine acyltransferase
d.-Diacylglycerol lipase
e.-Hormone sensitive lipase

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Great works are performed not by strength, but by perseverance.

  #2

a.-Acetyl CoA carboxylase & Hormone sensitive lipase are both activated by Insulin this is what i know
please do post the answer.


___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #3

Hey Jean whats the answer to this one.


___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #4

shaking head

  #5

The answer is A.

Of the enzymes on the list shown, only acetyl coenzyme A carboxylase directly produces a product, malonyl CoA, that is an allosteric regulator of another enzyme on the list. Malonyl CoA is the product of the first step in fatty acid synthesis, which occurs during a time of excess acetyl CoA due to satisfied energy and caloric needs of tissues.
Malonyl CoA allosterically inhibits carnitine acyl transferase I, which is the major regulatory enzyme of fatty acid oxidation. Fatty acid oxidation occurs during a time of energy need. Thus, when fatty acids are being synthesized during a time of “plenty,” the breakdown of fatty acids is shut off.

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Great works are performed not by strength, but by perseverance.







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