bright_nnn
Forum Senior
Topics: 17
Posts: 97
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the total time limit for PT ,aPTT, and Bleeding time?
What is their significance?
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| mistral92
Forum Senior
Topics: 4
Posts: 185
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BT is the screening test for primary hemostasis disorders..;such as lesion of vasculature; scurvy...thrombocytopenia...disorders of adhesion " Bernard SOULIER" , aggregation " GLANZMANN"....
the result of these perturbations is INCREASING BLEEDING TIME//// PT and PTT are?????? if it's just a problem with primary hemostasis....
PT and PTT are the screening test for secondary hemostasis
PT is the screening test for the extrinsic pathway ( factors 7....)
PTT is the screening test for the intrinsic path ( factor 8 factor 9, V.Willebrand factor....
some examples////
primary hemostasis disorders/
trombocytopenia.: " primary hemostasis disorders... increase BT. test platelet count. PT and PTT are ????
secondary hemostasis disorders///
for Hemophilia A " classic" : increase PTT///
PT and BT are???? remember its secondary hemostasis D/O
test is factor 8 assay.
hemophilia B.: "Christmas.H" increase PTT...
PT and BT are??? it is secondary hemostasis D/O
test is factor 9 assay.
mixed disorders///
DIC: increase BT increase PT and PTT and increase thrombin time or fibrinogen assay.
VW disease: increase PTT and BT/// PT is normal.
hope this will help you...good luck.
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| mistral92
Forum Senior
Topics: 4
Posts: 185
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in addition to above'
clinical presentation of primary hemostasis or platelet problem is petechiae and or purpura
test is BT and platelet count.
for secondary hemostasis or coagulation D/O: clinical presentation is generally deep tissue bleeding hemarthroses....test PT PTT.
VW factor : stabilizes factor 8 ; enables paltelet aggregation and enables platelet adhesion to endothelium this is why BT and PTT increased.
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| peekay
Forum Guru
Topics: 102
Posts: 588
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if u are asking about their ranges than estimately
pt=11-14 second
ptt=20-25 seoconds
bleeding time=3-10 minutes
any increase in their values would be due to many conditions , few of mentioned by mistal92
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