Vietnamese Forum Elite
Topics: 12 Posts: 285
| | 11/08/07 - 05:28 AM  
 
   
 
|   #2 |
Hi mate, Remember receptors Alfa-1,2 and Beta-1,2 is proteins in structure and the acidosis denaturalise these proteins, so these receptors get malfunctional under catecholamine effect. Vietnamese.
___________________ Nothing is impossible.
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| stak Forum Newbie
Topics: 4 Posts: 17
| | 11/08/07 - 06:03 AM  
 
   
 
|   #3 |
thanks vietnamease ! how about alkalosis? does alkalosis also affect alpha and beta receptors?
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| Vietnamese Forum Elite
Topics: 12 Posts: 285
| | 11/08/07 - 06:17 AM  
 
   
 
|   #4 |
Wow, Your question is pretty good, sorry I don't know exactly. But my hypothesis is as follow: the most common denaturalisation is the reason of acidosis, overheat, radiation..but never heard of alkalosis. Perhap it doesn't effect on receptor of catecholamine. Have a funny study. Vietnamese
___________________ Nothing is impossible.
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| stak Forum Newbie
Topics: 4 Posts: 17
| | 11/08/07 - 06:49 AM  
 
   
 
|   #5 |
hmm.. I see. I don't know overheat and radiation cause the same effects (; In case of ICU, low cardiac output syndrome with acute respiratory insufficiency cause hypotension and lactic acidosis. we should use sodium bicarbonate to correct pH before give catecholamine.
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