leftfoot
Forum Elite
Topics: 29
Posts: 216
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thanks!
but isnt mtoprolol beta one selective?
why will is hinder the beta two rec???
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| usmleasr
Forum Guru
Topics: 105
Posts: 970
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good q....any b1 selctive is not 100%...it is always beta1 more affinity than beta2...so there can be slight decrease in bronchodilation
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| sunman
Forum Newbie
Topics: 4
Posts: 19
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hmm...good point! i guess you are right.
there is no "all or none law" here.
thanks 
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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why can't it be propranolol ??
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| anne
Forum Elite
Topics: 41
Posts: 348
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bec propranolol is probably non-selective,and may cause much less bronchodilatation--here it says,slight decrease in dilatation.
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| Gul
Forum Elite
Topics: 9
Posts: 259
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Anne !! doesnt nonselective means, generalized action , i mean both beta1 and beta 2 actions ? so really, y not propranolol??
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| sk
Forum Senior
Topics: 23
Posts: 122
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Metaprolol....
The selective B1-blockers are BEAM....Betaxalol..Esmolol..Atenolol...Metaprolol.....all the rest are non selective and block both B1 and B2 receptors....
So if the drug X was Propanolol...there would be no response from the heart(B1) and there would have been no bronchodilation(B2) as propano. would block epi's effects there as well
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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thanks sk..
What about nadolol ??
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| sk
Forum Senior
Topics: 23
Posts: 122
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i forgot one drug in the B1 selective blockers ...Acebutol...
so its BEAAM....
....ur welcome asmi.... Nadolol,timolol are non selective B blockers.......
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| satheesh
Forum Junior
Topics: 7
Posts: 46
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it is physiological antogonism, but Propronolol appears to be the answer, i am not conviced. are you sure.
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satheesh
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