Q nephrotic syndrome

Prep for USMLE Forum

» Log in | Register

Forum

Step 1

Match

Prep4USMLE Forum » USMLE Step 1 Forum » Pathology Forum

Q nephrotic syndrome

Author

12 Posts

SmokyWaters
Forum Elite

Topics: 6
Posts: 447

10/28/07 - 02:55 PM

10 years old child developed severe proteinuria. Urine dipstick is positive. He has swelling of feet and abdomen. What is his renin and aldosterone values from normal?

1. increased
2. decreased
3. normal

smiling face

new_n_lost
Forum Hero
avatar

Topics: 663
Posts: 6,107

10/28/07 - 10:44 PM

Normal.

increased levels is an attractive choice but hasnt been proved. so i wud say normal for Renin and slightly increased for aldosterone.

I sincerely do hope i m right cos i havent started this topic yet. but keep the discussion going.

___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

icandoittoo
Forum Senior

Topics: 20
Posts: 73

10/29/07 - 11:38 PM

decreased level of renin and aldosterone.

SmokyWaters
Forum Elite

Topics: 6
Posts: 447

10/30/07 - 01:06 AM

whats the reason icandoittoo???

mikky
Forum Elite
avatar

Topics: 17
Posts: 430

10/30/07 - 01:14 AM

my choice is increased....
icf shits to ecf due to decreased cop.... so decreased perfusion of kidney...
kidney thinks hypovolaemia.... starts producing renin wh increases aldosterone...
hope i`m correct smiling face

___________________
it is our choices that show what we truly are, far more than our abilities!!!!

hope4dabest
Forum Elite
avatar

Topics: 19
Posts: 437

10/30/07 - 11:21 AM

increase renin and aldosterone...
nephrotic--->hypoalbunimeia---->shift of fluid to ICF--->Hypovolemia--->stimulation of renin-angiotenisn-aldosterone system

SmokyWaters
Forum Elite

Topics: 6
Posts: 447

10/30/07 - 12:08 PM

well I share the ideas of NNL... smiling face

there is no hypovolemia in nephrotic syndrome...ever heard of that??? grin

@ hope4dabest...
ICF fluid shifting isnt relevant...if you say its outside the VESSEL FLUID SHIFT then the person is normally hydrated...there is normal BP in the vessels of kidney...
always remember...
JG apparatus acts on fluid volume base...
if there is high amount of fluid passing through the renal tubule...it gives a negative signal to macula densa which gives signal to smooth muscles cells of afferent arterioles which produce renin...
intratubular fluid is normal unless there is renal failure...so renin is normal...

body controls blood pressure by NaCl...the normal SALT we eat...it doesnt have any other long term way to maintain that...proteins doesnt maintain blood pressure smiling face

even if we are severely hypoproteinemic as in kwashiorkor...there is no HIGH BLOOD PRESSURE smiling face

use common sense...dont go to the intricate details of every mechanism...

I just gave this question....to let u know that ...its the way they check on boards smiling face

best of luck

SILVER
DoWhatYouGotToDo!
avatar

Topics: 22
Posts: 870

10/30/07 - 01:21 PM

___________________
Expecting the world to treat you fairly because you are a good person, is like expecting the lion not to attack you because you are a vegetarian.

SmokyWaters
Forum Elite

Topics: 6
Posts: 447

11/17/07 - 11:39 PM

sorry guys .. ITS INCREASED... I am sorry for the wrong explanation

new_n_lost
Forum Hero
avatar

Topics: 663
Posts: 6,107

11/18/07 - 05:05 AM

#10

SmokyWaters wrote:
sorry guys .. ITS INCREASED... I am sorry for the wrong explanation

Hmmm Interesting can u plz elaborate ??

___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

imnalini
Forum Senior

Topics: 10
Posts: 127

11/21/07 - 05:03 AM

#11

INCREASED------

edema = increased fluid in interstitial fluid = decreased effective arterial blood vol =
decreased renal perfusion = increased renin n aldosterone.

cirus
Forum Guru
avatar

Topics: 108
Posts: 740

11/21/07 - 12:17 PM

#12

imnalini wrote:
INCREASED------

edema = increased fluid in interstitial fluid = decreased effective arterial blood vol =
decreased renal perfusion = increased renin n aldosterone.

You don't have permission to post.