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Kaplan Qbank USMLE



Author20 Posts
  #1

What does this mean?
HCV AB negative
HCV AG negative
HCV RNA positive
what is your next step?




Good luck


___________________
AAzad

  #2

options? pasting whole question would be better, but at least give options!!wink

___________________
Man who fights too long against the dragons becomes a dragon himself.

  #3

I want your exact Dg and next step , it is a real case.
Thank you for your response and
Good luck


___________________
AAzad

  #4

Window phase in acute HCV ? raised eyebrow

___________________
"أقرأ بأسم ربك الذي خلق,خلق الأنسان من علق,أقرأ و ربك الأكرم, الذي علم بالقلم,علم الأنسان ما لم يعلم"

  #5

could be , what is your next step?

___________________
AAzad

  #6

Measure Liver Enzymes , if High Give ttt?rolling eyes

___________________
"أقرأ بأسم ربك الذي خلق,خلق الأنسان من علق,أقرأ و ربك الأكرم, الذي علم بالقلم,علم الأنسان ما لم يعلم"

  #7

Anti-HCV (antibodies to the virus) may not be present in the first four weeks of infection.
HCV-RNA and RT-PCR tests can determine HCV presence in as little as 1-2 weeks.

Therefore, the diagnosis is early HCV infection.


The next step will be liver function measurement. Not treatment.


  #8

active heaptitis No treatment

  #9

HCV RNA is the first test would be positive in acute HCV.

it could be positive while other markers are negative .

Tx : interferon and lumavudine

  #10

I agree with everyone about the serologic markers pointing HEP C ACUTE INFECTION but at this point supportive treatment is the mainstay and the use of antiviral therapy is not defined. But i think the next step should be evaluate liver profile, concomitant infection(HIV, hep C, etc), h/o alcoholism, comorbidities.

I read that the indication for treatment is: increased ALT and active inflammation and some fibrosis on biopsy but I don't know when biopsy is indicated.


___________________
If you beleive you can do it then you WILL DO IT!! (by Mymeghhi)

  #11

excellent all of you ,but , why did not any of you suggested Viral load /quant test/pcr(only drdg suggested pcr).
waiting


___________________
AAzad

  #12

  • Quantitative assays are available, but HCV viral load has not been definitively shown to be useful in predicting outcome (unlike HIV viral load).
    http://www.emedicine.com/ped/topic979.htm#section...


    ___________________
    If you beleive you can do it then you WILL DO IT!! (by Mymeghhi)

  •   #13

    Excellent

    ___________________
    AAzad

      #14

    AAzad wrote:
    Excellent


    Good thought provoker!


    ___________________
    Smell the coffee! "Is That an Osler move??"

      #15

    what else ?
    lets keep it up . what else?


    ___________________
    AAzad

      #16

    INF alfa is used in acute Hepatitis C,
    I suggest also this patient may have cryogobulinemia.
    Any ideasraised eyebrow

    ___________________
    "أقرأ بأسم ربك الذي خلق,خلق الأنسان من علق,أقرأ و ربك الأكرم, الذي علم بالقلم,علم الأنسان ما لم يعلم"

      #17

    HCV RNA is the first test would be positive in acute HCV.

    it could be positive while other markers are negative .

    Tx : interferon and lumavudine


    ---> isn't it ribavirin instead?

      #18

    interferon and ribavirin are the Tx for HCV.

    ___________________
    Never give up!!

      #19

    ok you are all correct , but this patient on hcv RNA viral load showed undetectable , what does that meaN/what to do now?

    ___________________
    AAzad

      #20

    how about all of these 99 scorers?


    ___________________
    AAzad







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