njcjzy
Forum Guru
Topics: 18
Posts: 729
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A 28-year-old female comes to the emergency department with a headache and fever. She has not had any recent infections, nor has she been exposed to any drugs. Her medical history is unremarkable. On examination, the patient appears lethargic. Her temperature is 100.5 F, pulse is 100/minute, blood pressure is 130/85 mm Hg, and respirations are 18/min. Her conjunctivae are yellowish, and scattered petechiae are noted on the lower extremities. The liver and spleen are not enlarged.
Laboratory studies show the following results: WBC 12,000/mm3; hematocrit 27%; platelets 14,000/mm3; bilirubin 4.5 mg/dL; direct bilirubin 0.5 mg/dL; BUN 40 mg/dL; creatinine 3.5 mg/dL. PT, fibrinogen, and PTT are all normal. Her peripheral blood smear shows fragmented red blood cells.
What is the most effective treatment for this patient?
(A) Splenectomy
(B) Glucocorticoids
(C) Plasmapheresis
(D) Intravenous immunoglobulins
(E) Platelet transfusion
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| Kamsi
Forum Guru
Topics: 103
Posts: 347
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C
pt has TTP and plasmapheresis id d most effective tx
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| Ivonne
Forum Guru
Topics: 57
Posts: 1,519
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C.....................TTP
___________________
"The question isn't who is going to let me; it's who is going to stop me. " ~ Ayn Rand
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| dr.wad
Forum Senior
Topics: 3
Posts: 345
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C
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| sprint123
Forum Guru
Topics: 129
Posts: 870
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 ..Agreed...I was just wondeing what might be the cause of TTP in this patient? Since no history is given specifically related to the cause, what might be the common cause if TTP??Is it idiopathic?
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| njcjzy
Forum Guru
Topics: 18
Posts: 729
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Yes, the answer is C.
Sprint123, please read this link for the potential causes of TTP.
http://en.wikipedia.org/wiki/Thrombotic_thrombocy...
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