icandoittoo
Forum Senior
Topics: 20
Posts: 73
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A 40 y.o. male presents with headache, weakness and weight gain.PE reavelas puffiness of the face and BP 160/75 mm Hg, fasting plasma glucose 200mg/dl,serum Na 150 mmol/L,serum K 3.1 mmol/L. His plasma cortisol level is High. Administration of low and high dose of cortisol fail to suppress the plasma cortisol level.His plasma corticotrpin is 0.8 pg/ml. In this patient,which of the following lesions is mot likely ?
a.-Adenoma of right adrenal cortex with atrophy of contralateral adrenal cortex
b.- Small cell carcinoma of the lung
c.-a corticotroph adenoma of anterior pituitary
d.-Adenoma of right adrenal cortex without atrophy of contralateral adrenal cortex
e.-Corticotroph adenoma of ant.pituitary,medullary carcinoma and bilateral nodular hyperplasia of adrenal cortex
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| sfk
Forum Elite
Topics: 43
Posts: 294
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A
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Forum Elite, But Step 2 Newbie....
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| paheli
It'sAllAboutGoodKarma
Topics: 170
Posts: 2,217
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can you please explain how to differentiate b/w A and D?
thanks.
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Prepare as if you're the worst, Perform as if you're the best! As you dream, so you manifest. So, DREAM BIG!! When you face hardship, remember, God never gives you more than you can handle. Keep your face to the sunshine and you cannot see the shadows.
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| new_n_lost
Politically InCorrect
Topics: 650
Posts: 6,058
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Negative feedback loops amongst the 2 organs just like if Renin interaction in a constricted Kidney.
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| paheli
It'sAllAboutGoodKarma
Topics: 170
Posts: 2,217
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i should have known that!
thanks a lot, nnl!
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Prepare as if you're the worst, Perform as if you're the best! As you dream, so you manifest. So, DREAM BIG!! When you face hardship, remember, God never gives you more than you can handle. Keep your face to the sunshine and you cannot see the shadows.
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| icandoittoo
Forum Senior
Topics: 20
Posts: 73
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 Good job, guys. Correct ans. is A
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| icandoittoo
Forum Senior
Topics: 20
Posts: 73
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Let s repeat in other words what nnl has explained very well
1.-Glucocorticoid secretion from an adrenal neoplasm suppresses corticotropin production by the pituitary, which leads to atrophy of the contralateral adrenal cortex.
2.-An adrenal cortical adenoma that secretes aldosterone doesn t cause atrophy of the contralateral adrenal cortex.
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| SmokyWaters
Forum Elite
Topics: 6
Posts: 458
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whys there headache?
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| SmokyWaters
Forum Elite
Topics: 6
Posts: 458
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n since when cortisol suppression test has been used to diagnose this condition?
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| SmokyWaters
Forum Elite
Topics: 6
Posts: 458
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anyways..its A.. alright 
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