asmi
Forum Hero
Topics: 1043
Posts: 4,609
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how do you detect clinically ??
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| bright_nnn
Forum Senior
Topics: 17
Posts: 97
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Thiamine def. is detected clinically in Wenicke=there is Ataxia Ophthalmoplegia and nystagmus
Korsakoff=there is Confabulations
Wet BeriBeri=in which the heart shows massive cardiomegaly(dont know why)
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| jayesh
Forum Junior
Topics: 2
Posts: 46
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clinically thiamine deficiency may present as wet/ dry beri beri
wet beri beri involves heart , where there will be high cardiac output failure, edema will be present CHF
dry beri beri peripheral neuropathy,
wernicke encephalopathy ataxia, nystagmus ophthalmoplegia
korsakoff's psychosis confabulation and memory loss
i remember only these, please add any other features
jayesh
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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you all are correct 
Actually i should have written laboratory confirmation for thiamine def...and its transketolase enzyme measurement .
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| satheesh
Forum Junior
Topics: 7
Posts: 46
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why dont we estimate alpha keto glutarate, Pyruvate dehydrogenase, Branched chain keto acid dehydrogenase. Eventhough RBC has no mitochondira, why did they estimate only Transketolase for Thiamine deficiency :!: :shock: :shock:
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satheesh
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| Bela
Forum Guru
Topics: 76
Posts: 412
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Maybe transketolase was the only answer choice in the question stem 
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La vita e bella!
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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:wink:
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