DrVirgo
Forum Hero
Topics: 1058
Posts: 3,385
|
High Insulin & High C-peptide: Insulinoma
High Insulin and LOW C-peptide: surreptitious Insulin injection
(because Insulin and C-peptide made together)
Low Insulin and HIGH C-peptide??? Not sure
(Insulin is made and C-pepdide is what is left when Insulin is cleaved off from its precursor)
Whats the answer?
___________________
Our greatest glory is not in never falling, but in rising every time we fall.
|
| Doc750
transfer:step 3 prison
Topics: 52
Posts: 636
|
C peptidonoma 
___________________
Experience is a hard teacher because she gives the test first, and the lesson afterwards.
|
| drgeorgie
Forum Senior
Topics: 22
Posts: 149
|
for real?????
___________________
"The army saw Goliath as too big to hit. David saw him as too big to miss!"
|
| DrVirgo
Forum Hero
Topics: 1058
Posts: 3,385
|
Yes, Doc750 won the Nobel Peace prize for discovering it!
___________________
Our greatest glory is not in never falling, but in rising every time we fall.
|
| dr.roh
Forum Guru
Topics: 159
Posts: 361
|
this is an actual question that was on someone elses exam
|
| DrVirgo
Forum Hero
Topics: 1058
Posts: 3,385
|
What are the levels of Insulin and C-Peptide in:
DM-I?
DM-II?
how about pregnancy? hPl is an anti insulin, in this case would insulin be low and c-peptide be high? (just guessing)...
___________________
Our greatest glory is not in never falling, but in rising every time we fall.
|
| ing
Forum Guru
Topics: 45
Posts: 435
|
DM_I: insulin low, C-pep low
DM II: insulin and c-pep normal or high?
pregnant: same as DM-II. ?
___________________
Never give up!!
|
| aaroho
Forum Junior
Topics: 8
Posts: 75
|
Diabetes 45:1010-1015, 1996
© 1996 by the American Diabetes Association, Inc.
Low insulin secretion and high fasting insulin and C-peptide levels predict increased visceral adiposity. 5-year follow-up among initially nondiabetic Japanese-American men
ABSTRACT
Insulin resistance and hyperinsulinemia occur more frequently in subjects with greater visceral adiposity, but it is not known whether these metabolic abnormalities precede or follow visceral fat accumulation. We prospectively studied the development of visceral adiposity in relation to fasting and stimulated insulin and C-peptide levels. We followed 137 nondiabetic, second-generation Japanese-American men for changes in visceral adiposity over 5 years. Intra-abdominal fat (IAF) area (square centimeters) was measured at the umbilicus by computed tomography at baseline and after 5 years. Plasma insulin and C-peptide levels were measured after an overnight fast and during an oral glucose tolerance test. Beta-cell function was measured by the insulin secretion ratio (30-0 min plasma insulin difference)/(30-0 min plasma glucose difference). After adjustment for baseline IAF in multiple linear regression models, baseline fasting insulin (coefficient = 0.241, P = 0.048) and C-peptide (coefficient = 38.538, P < 0.001) levels were positively correlated, while the baseline insulin secretion ratio was negatively correlated with IAF change (coefficient = -0.099, P = 0.027). With IAF difference coded as a dichotomous variable (> 0 cm2 vs. < or = 0 cm2), the highest versus lowest tertile of baseline fasting insulin (odds ratio [OR] = 3.0, 95% CI 1.0-9.7) and fasting C-peptide (OR = 8.1, 95% CI 2.4-26.8) levels and the lowest versus highest tertile of the insulin secretion ratio (OR = 3.3, 95% CI 1.0-10.0) were associated with higher odds of IAF gain. Greater insulin resistance and reduced insulin secretion precede visceral fat accumulation in nondiabetic Japanese-American men.
___________________
Life is wonderful when doctors all around
|
|
| |
| | | | | | | | |
