peraspera
Forum Elite
Topics: 38
Posts: 233
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A maintenance worker is inadvertently exposed to the fuel core in a nuclear power plant accident. This 40-year-old man has received an estimated 9 Gy of total-body irradiation. He is brought to the emergency room. The most appropriate statement concerning the current situation is:
(A) The patient will likely die within 48 h of acute
neurologic and cardiovascular failure.
(B) The patient will experience a transient drop in his
white blood cell and platelet count.
(C) Problems are not likely to develop at this level of
exposure.
(D) The patient will require intensive supportive care,
including bone marrow transplantation.
(E) Intensive fluids and gastrointestinal support will
suffice
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| aaroho
Forum Junior
Topics: 8
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D
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| kpmle2
Forum Elite
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(A) The patient will likely die within 48 h of acute
neurologic and cardiovascular failure.
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| hanialkhadher
Forum Elite
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A-
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| peraspera
Forum Elite
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Posts: 233
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The answer is D.
The effects of total-body irradiation on the human are
dose-dependent. Doses >100 Gy result in death within 48 h due to neurologic and cardiovascular collapse. Doses >5 Gy produce denudation of the gastrointestinal mucosa and result in death due to dehydration and sepsis unless aggressive supportive care is provided.
The marrow component is even more sensitive than the gastrointestinal tract, with doses>2 Gy causing significant cytopenias. The marrow may recover in time (i.e., without a transplant) at doses <8 Gy; yet doses >10 Gy are often fatal due to gastrointestinal
problems even with supportive care. Therefore marrow transplantation may be most reasonable for individuals exposed to total-body doses of 8– 10 Gy.
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| Doc750
transfer:step 3 prison
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good question
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