logitech
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In mucolipidosis II (I-cell disease), the enzyme catalyzing formation of mannose 6-phosphate, the signal for transfer to lysosomes, is missing. Proteins destined for the lysosome are most likely to be found in which of the following locations in patients with this disease?
A) Endoplasmic reticulum
B) Extracellular space
C) Golgi complex
D) Mitochondria
E) Nucleus
Edited by new_n_lost on 10/09/07 - 05:38 PM. Reason: Plz Atleast write the question correctly and in the right font
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| new_n_lost
Politically InCorrect
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C) Golgi complex
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| madoo
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phosphorylation on mannose rseidues of lysosomal enzymes occurs in golgi and because of this the lysosomal enzymes is direct to the lysosomes
but if phosphorylation didnt happen the lysosomal enzymes will not be directed to lysosomes and will be released into the extracellular space
"B) Extracellular space "
Edited by madoo on 10/09/07 - 08:57 PM
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| Ujk
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B
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| sfk
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Yes Answer is B.
Good explanation by madoo
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