Justice
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B. propylthyouracil therapy with the goal of maintaining her thyroid function tests in the high-normal or slightly high range
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| hanialkhadher
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B
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| sukhs
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D... why high normal state is required?
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| dr.wad
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B_the least possible dose of prpylthyuracil should be used.
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| Kamsi
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D
Why not mid normal range
What's d answer?
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| peraspera
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Answer B.
Radioactive iodine should never be given to a pregnant woman. In addition, both methimazole and beta blockers should be avoided in pregnant women. Methimazole may lead to an increased incidence of aplasia cutis, a fetal scalp defect. Beta blockers may lead to neonatal hypoglycemia.
Antithyroid drugs, including propylthiouracil, cross the placenta and affect fetal thyroid function. Studies have shown that when a treated pregnant woman’s thyroid function is in the mid-normal range, the fetus is hypothyroid. When the mother’s thyroid tests are maintained in the high-normal or slightly hyperthyroid range, the fetus is likely to have normal thyroid function. Severe maternal hyperthyroidism is potentially dangerous for the fetus, but mild maternal hyperthyroidism poses a much smaller risk.
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