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 Kaplan Q  



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Author14 Posts
  #1

Hmmmm..... what do yo think?





  #2

A


  #3

No, someone else, please with an explanation.


  #4

then its E. i say so by ruling out other options coz it cant be Ig or immune complexes


  #5

Well that what Kaplan book says, but if you have a Big Robbins (Pathologic basis of disease 7 ed. ) and read chapter on Myasthenia Gravis, you would be surprised. ( Page 1344)

It's not E.



  #6

B??


  #7

Yes, It's B.


  #8

It is B.. Autoimmune destruction of postsynaptic ACh receptors; MG


  #9

I'm wondering, is there any destruction or it is just a blocking antibody?
I think It is TypeII HSR but noncytotoxic.
If you check on Kaplan Medical Note Book Immunology page 445 table II-13-7 it is clearly written that there is no comlement or effector cells contripution..
I quess the true answer is not there in the choices and they made a mistake, but at the end it is the Best answer we are looking for and we can say B as it is the nearest to truth although it is far away..

If I'm wrong.. would any one kidly correct me.


  #10

I checked out and I think it is incomplete table that I mentioned be4 and the Complement activation is implicated in the pathogenesis od Myesthenia Gravis.. It is B the best and correct answer, as the blocking antibodies also activate the complement and form MACs and destruction.
any additions or corrections are appreciated.


  #11

good question GG anybody cud fall for trap whether block or MAC at ach receptor.thanks for sharing!but i chose b when did it wink


  #12

GG , you means kap give wrong answer , then u better write to them . Since I am not having time now adays , so in Qs I might rush , if wrong , will read explaination instead of go to big text , but are we all sure any texts or mid size books or any are right for sure.
Now a days , what disturb me alot is , like FA , KME , kap LN , RR path etc almost all famous books have error but we never know until we discuss here or with frds or found the error on line in other forums or some here .
But now ur saying it Q banks or kap Qs have error too , so how abt UW , chnaces are error will b there too. God help us, have mercy , who will have time to go for every qs, notes , books to recheck with big texts , even , is the big texts are error free 100% at all , like God we said in RR path is not error free , so did Fa as bible [ God for st 1] also has tons of error .sadmad

Thanks GG , have more coming , so we will notice read every answer with the caution .

GL GL GL happy success study to us , all nodcoolnod


  #13

yes complement activation is implicated in myasthenia gravis but no complement activity in type 1 hypersensitivity......


  #14

it looks like a case of myasthenia gravis and its antibody against Ach receptor so C





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