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 E cadherin  




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Author9 Posts
  #1

what is its function ?


  #2

tough q
adhesion?


  #3

its needed to form epithelial junctional complexes containing zona occludens ,zona adherens and desmosomes.[/b]


  #4

about zona adherens, I agree that contains E-cad. linked with actin filaments; but about tight jonction and desmosomes...
desmosomes contain tonofillaments and attachment plaques and desmoplakin,-glein,...where is the place for E-cad.?
but in tight j.? :oops:


  #5

can someone tell me few facts ab desomosomes/zona occludens n adhgerens n tight junctiopns, i have already forgotten even before writing my exam :oops:


  #6

Zone occludens - tight junctions-prevents diffusion across intracellular space.
Zone adherens - intermediate junction - surrounds perimeter just below zone occludens
Macula adherens (desmosomes) - small sites of attachment
Gap junction - allows adjacent cells to communicate for electric and metabolic functions
E cadherin is attached to zone adherens and so are actin filaments
Integrin attaches hemidesmosome which connects cells to underlying extracellular matrix

This info is from first aid!!!


  #7

E Cadherin also known as A-CAM....as the name implies it is seen in Zona adherens....I have no clue what its used for.....for bacterial adherence to cross over is my wildest guess!!!


  #8

Basically the adherins are connecting adjacent cells together!!! Ecadherin supports Zona adherens.


  #9

SUPPORT CONTACT BET CELLS,,,,,,WHEN CANCER INVADE TISSUE IT DESTROY CADHREN TO AID ITS INVASION





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