silver wrote:
Normally, sodium voltage gated channels are guarded by calcium in order to repel sodium so that there isn't too much influx of sodium. However, in hypocalcemia, calcium levels decrease in interstitial fluid and blood, so the calcium guarding the sodium voltage gated channels compensate the decreased levels, thereby rendering these sodium volt. gated channels 'unguarded', so there's excessive influx of sodium. action potential is easily produced, because RMP reaches threshold faster and tissue becomes hyperexcitable.
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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