elitoki
Forum Guru
Topics: 54
Posts: 508
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M2 : a lot of myeloblasts on peripheral blood film .
M3: (DIC) a lot of hypergranular promyelocyte with Auer Rods
M5: has monoblasts without Auer Rods
promonocytes
monocytes
PAS -
...esterase +
Could help me to complete this ?
thanks.
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| elitoki
Forum Guru
Topics: 54
Posts: 508
|
M1 (myelocytic) without differentiation. A substantial proportion of cells are myeloperoxidase-positive; few cells mature beyond the myeloblast stage.
M2 (AMLwith maturation) > 30% blasts, with more than 50% of the blasts being myeloblasts and promyelocytes. Mature forms are seen as well. Eosinophils may be heavy in some cases.
M3 (APML) > 30% blasts. The majority of cells have a promyelocytic appearance with kidney-shaed nuclei. Auer rods are usually seen in the cytoplasm.
M4 (Myelomonocytic) >30% blasts, with promonocytes and monocytes accounting for more than 20% of the bone marrow aspirate.
M5 (Monocytic) > 30% blasts; the granulocyte component is less than 10% of marrow cells. The monocytes can be detected cytochemically with the fluoride-sensitive esterase reaction
M6 >30% blasts, of which more than 50% are erythroblasts
M7 (Megakaryocytic) In this condition, blasts react with antiplatelet antibodies.
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