asmi
Forum Hero
Topics: 1043
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How do you differentiate both ?
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| merjr
Forum Junior
Topics: 1
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Both have problem in platelet adhesion and aggregation.
In Bernard Soulier there is increased BT ,moderate thrombocytopenia and Giant megakaryocytes are present. treatment is difficult and platelet transfuion may be given.
In vWD prolonged BT, PTT, and treated with desmopresin
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| Gul
Forum Elite
Topics: 9
Posts: 259
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vWD Disease:
Deficiency of Von Willebrand Factor. Defect of platelet adhesion
:arrow: Inc. BT
:arrow: Inc. PTT
:arrow: Functional deficiency of Factor VIII
Bernard Soulier:
Defect of Platelet adhesion
:arrow: Normal platelet count but inc.BT
:arrow: large platelets
:arrow: There is lack of platelets surface glycoprotein GPIb-IX
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| asmi
Forum Hero
Topics: 1043
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good job..thanks to both
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| usmleasr
Forum Guru
Topics: 105
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we differentiate both by the fact..BT...bernaud soulier improves with platlet transfusion....(normal platlet replacement)...while VWF will not improve
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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yep vWD will improve with cryopreciptitate.....
.....HCV most commonly trasferred via cryopptate.
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