medocuk
IM-RES
Topics: 26
Posts: 1,499
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DNA of both parents of a child with Down's has been studied. A cloned DNA when used as a probe reveals a RFLP in the region adjacent to the centromere of chromosome 21. Four haplotypes exist. A B C D. Genotype of father is AC Mother BD and that of child is ABC. Non juntion most likey occured in.
1.child during the first mitotic division.
2. father during meiosis 1
3. father during meiosis 11
4. mother during meiosis 1
5. mother during meiosis 11
I know the answer, I want to know how we come to that conclusion. Thanks for your help.
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| Jackofknives
Ipwnpoker.com
Topics: 91
Posts: 708
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2. right?
its obviously the father, since 2 chromosomes of different RFLP types are from the father.
In order to inherit 2 different RFLP types, there should be non disjunction during meiosis I. Whereas in meiosis II, either AA or CC is inherited.
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| SmokyWaters
Forum Elite
Topics: 6
Posts: 458
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quite right buddy 
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| SmokyWaters
Forum Elite
Topics: 6
Posts: 458
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quite right buddy
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