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Kaplan Qbank USMLE



Author3 Posts
  #1

There is a question in UW about a 48 year old white female status post radical mastectomy for breast cancer, 9 months ago, who on examination today is found to have a 2.0 cm pulmonary nodule on chest x-ray. Patient is asymptomatic. CT is done and biopsy shows adenocarcinoma with positive estrogen receptors with no HER-2/neu overexpression. What is the best step in management?

They give the answer as surgery, but according to my Blueprints OB/GYN the treatment of estrogen receptor positive metastatic breast cancer in the premenopausal woman is tamoxifen. Is this UW question outdated? My book also says combination chemo if estrogen receptor negative and oophorectomy or GnRH antagonists if premenopausal estrogen receptor positive.


  #2

I guess it would be corresct to remove this single solid mets, and then stick to chemo+hormon therapy

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  #3

You're right Justice, that's the course of the treatment according to the current guidelines.


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