new_n_lost
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In which of the following sites do myxopapillary ependymomas most frequently occur?
A. Cerebellum
B. Conus medullaris
C. 4th ventricle
D. Lateral ventricles
E. Midbrain
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| angel^Doctor
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C 
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| GoodGirl
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C
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| new_n_lost
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 Think again on this One Guys
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| GoodGirl
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Must admit, I cheated, had to look it up.
So now I know the answer is : B
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| angel^Doctor
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ya me 2, robbns page 347, 6th edition :
" myxopapillary ependymoma occur in filum terminalis of the spinal cord"
so B
it is the SUBEPENDYMOMA tupe that occur more often in 4th and lateral ventricles!
in first two decades of life>> most comon site is 4th ventricle
in adults >> most common site is spical cord
intresting!
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| new_n_lost
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Sorry for the late posting guys .
The correct answer is B.
Myxopapillary ependymoma is a variant of ependymoma, a tumor arising from ependymal cells. Histologically, myxopapillary ependymoma contains a myxoid (mucus-rich) intercellular matrix, in which spindly neoplastic ependymal cells are arranged in a fascicular and papillary pattern (hence its designation). It is a benign tumor that almost always occurs in the distal segment of the spinal cord, ie, the conus medullaris. Once excised, the patient is cured.
The cerebellum (choice A) is the favorite site for pilocytic astrocytomas, medulloblastomas, and hemangioblastomas, but not ependymomas.
In general, classic ependymomas occur in close proximity to the ventricular cavities, specifically, the 4th ventricle (choice C) in children and the lateral ventricles (choice D) in adults. The myxopapillary variant does not occur in either location.
A midbrain location (choice E) would be truly exceptional for any type of ependymoma.
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| macintosh
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This is a confusing question. How am I suppose to differiantiate between myxopapillary and classic ependymoma?
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| spinal shock
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thanx new_n_lost that was a great Q.
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| PhotoMom
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"Myxopapillary ependymoma is a variant of ependymoma, a tumor arising from ependymal cells. Histologically, myxopapillary ependymoma contains a myxoid (mucus-rich) intercellular matrix, in which spindly neoplastic ependymal cells are arranged in a fascicular and papillary pattern (hence its designation). It is a benign tumor that almost always occurs in the distal segment of the spinal cord, ie, the conus medullaris. Once excised, the patient is cured."
Not true. ME's can occur anywhere in the spinal cord. Once excised, they're not cured. ME's have a propensity for seeding and recurrence, often many years later - some studies put the recurrence rate as high as 45% with total en bloc excision, and as high as 80% with piecemeal excision. They do not generally respond well to radiation therapy, and have been know to metastasize throughout the the CNS.
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| new_n_lost
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PhotoMom wrote:
"Myxopapillary ependymoma is a variant of ependymoma, a tumor arising from ependymal cells. Histologically, myxopapillary ependymoma contains a myxoid (mucus-rich) intercellular matrix, in which spindly neoplastic ependymal cells are arranged in a fascicular and papillary pattern (hence its designation). It is a benign tumor that almost always occurs in the distal segment of the spinal cord, ie, the conus medullaris. Once excised, the patient is cured."
Not true. ME's can occur anywhere in the spinal cord. Once excised, they're not cured. ME's have a propensity for seeding and recurrence, often many years later - some studies put the recurrence rate as high as 45% with total en bloc excision, and as high as 80% with piecemeal excision. They do not generally respond well to radiation therapy, and have been know to metastasize throughout the the CNS.
Any references ??
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