new_n_lost
Politically InCorrect
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A 60-year-old male with angina comes to the emergency room with severe chest pain unresponsive to sublingual nitroglycerin. An EKG shows ST segment elevation in the anterolateral leads, and thrombolytic therapy is initiated.
If streptokinase is given to this patient, it may produce thrombolysis after binding to which of the following proteins?
A. Antithrombin III
B. Fibrin
C. Plasminogen
D. Protein C
E. Thrombomodulin
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| yoga
usmlelogy professor
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c?
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| hope4dabest
Forum Elite
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C
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| Ujk
Forum Guru
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C
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| medocuk
IM-RES
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C it is. 
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| amritt786
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C
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| new_n_lost
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yoga wrote:
c?
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| new_n_lost
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The correct answer is C.
The fibrinolytic activity of streptokinase is due to its ability to bind and cleave plasminogen, producing plasmin. Plasmin directly cleaves fibrin, both between and within the fibrin polymers, thus breaking up thrombi and potentially restoring blood flow to ischemic cardiac muscle. This same mechanism of fibrinolysis is shared by urokinase and tissue-plasminogen activator (tPA).
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