jayesh
Forum Junior
Topics: 2
Posts: 46
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hi
i have a question on hapten carrier complex....can any one explain how?
penicillin is hapten, BSA is carrier and egg albumin is also carrier
A mouse was injected with pen-BSA (covalently bound) and at the same time egg albumin with no pen is also injected. which will induce secondary response to penicillin when injected 1 mth later
a) penicillin
b) pen-egg alb
c) egg alb
d) BSA
jayesh
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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i think its egg albumin
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| phanul75
Forum Newbie
Topics: 0
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Hi. I'd say B. Pen-BSA.
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| asmi
Forum Hero
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what is BSA ? :roll:
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| jayesh
Forum Junior
Topics: 2
Posts: 46
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the answer is BSA- bovine serum albumin
it cannot be penicillin, becos its a hapten it cannot trigger imm response
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| asmi
Forum Hero
Topics: 1043
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ok
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| krsma
Forum Elite
Topics: 40
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i dont' understand this question, maybe it's just me
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| Quinn
Forum Elite
Topics: 63
Posts: 308
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My understanding is that when the pen-BSA complex was injected 1mth ago antibodies were produced that bind both BSA epitopes and to pen. Also, it is possible....likely that seperate antibodies to egg alb were form. If you want to know what would happen if you inject pen now, the best answer would be "a" penicillin . It could not be "b" because no pen-egg alb antibodies were formed....not "c" because the egg-alb would not cause a second response in someone injected with only penicillin....and "d" might be a likely second choice, but not the best answer in this case because BSA was not injected...we are told that penicillin was injected.
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| jayesh
Forum Junior
Topics: 2
Posts: 46
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hello Quinn
actually this question was taken from Jawetz review...
the answer given is BSA, but no explanations
the choice B and C r not correct
choice A is penicillin, its a hapten a hapten alone cannot trigger immune response , it mus be bound with a carrier ( carrier has many antigenic determinants)......so the choice wud be B. BSA
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| Quinn
Forum Elite
Topics: 63
Posts: 308
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Hi Jayesh,
You are right :cry: ....brain fart on my part. Nice question. 
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