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Author8 Posts
  #1

A researcher is examining the distribution of an ion channel protein in the kidney. She incubates slices of kidney tissue in a dilute solution of a specific antibody directed against the protein, then uses the immunoperoxidase method to localize the ion channel proteins. She notes the presence of brown pigment in a population of epithelial cells, which on closer examination, have a brush border.

The researcher concludes that the protein is probably present in cells of the

A. Collecting duct
B. Deep portion of loop of Henle
C. Distal convoluted tubule
D. Glomerulus
E. Proximal convoluted tubule


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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #2

E. Proximal convoluted tubulenodnodnod

  #3

ppl U never know they might ask u things like These so give it a try !!!

___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #4

shockedshocked >> Wht No One shockedshocked

___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #5

po wrote:
E. Proximal convoluted tubulenodnodnod

nodnod

___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #6

The correct answer is E.

The immunoperoxidase method uses horse-radish peroxidase to produce a visible pigment when a specific antibody binds to antigenic sites in the tissue. Binding of the antibody to the epithelial cells indicates that the protein in question is being expressed by those cells. The positive immunoperoxidase results obtained here suggests that the channel protein is expressed in proximal convoluted tubular epithelium, since this is the only site in the kidney at which the epithelial cells have a "brush border." The brush border is made of microvilli, which enhance the proximal tubules' ability to reabsorb plasma constituents filtered at the glomeruli.


___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #7

nod

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“When a person really desires something, all the universe conspires to help that person to realize his dream.”

  #8

brush border=PCT-dont panic since it looks like a Q from molecular bio but it is give a away qnod







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