doyoudig
Forum Guru
Topics: 144 Posts: 610
| | 08/23/07 - 11:01 AM  
 
|   #1 |
Since it is anti-estrogen, it causes Post M Symtpomsa such as vaginal dryness and hot flashed, so why is the Pt at increased risk of endometrial hyperplasia????????
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| elitoki
Forum Elite
Topics: 21 Posts: 225
| | 08/23/07 - 12:33 PM  
 
|   #2 |
Tamoxifen is selective estrogen receptor modulador(SERM) and it has agonist and antagonist effect. Tamoxifen is more agonistic in uterus than in breast so it will stimulate endometrial growth and will antagonist the breast cancer receptor.
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| NNL
Awaitin The Unexpected

Topics: 779 Posts: 6,627
| | 08/23/07 - 05:08 PM  
 
|   #3 |
 
___________________ Tyrants and Occupiers of territories tend to think, act and feel alike "Never argue with fools, they'll bring you down to their level & beat you with experience" “The Pure and Simple Truth is RARELY Pure and Never Simple" It is with words as with sunbeams, the more they are condensed, the deeper they burn Would You Dare to Think Different PS I get enough exercise just by pushing my luck
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