losartan

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losartan

Author

6 Posts

asmi
Forum Hero

Topics: 1043
Posts: 4,609

03/14/04 - 01:43 PM

what is the MOA ?

Colombia
Forum Guru

Topics: 85
Posts: 438

03/14/04 - 01:48 PM

Antagonist of angiotensin :?:

jb00727
Forum Elite

Topics: 82
Posts: 190

03/14/04 - 02:00 PM

losartan is a type1 angiotensin2 receptor antagonist

asmi
Forum Hero

Topics: 1043
Posts: 4,609

03/14/04 - 02:30 PM

yes its a competitive antagonist of AT-1 receptor ....thus blocks effects of angiotensin II .BUT donot affect BK levels .

:idea: can be used for a pt on ACEI develops persistent dry cough

step1taker
Forum Senior

Topics: 2
Posts: 105

03/15/04 - 12:36 AM

"jb00727" wrote:
losartan is a type1 angiotensin2 receptor antagonist

why is LOSARTAN type1?is there a type 2?

Pls.enlighten me thanks in advance smiling face

What I know is LOSARTAN is an angiotensin 2 receptor blocker (ARB) that does not cause cough because it doesnt inhibit kininase (which destroys bradykiinin-causing cough)unlike ACE inhibitors.

Im not aware of a type 1 or type 2 AT2 receptor blocker. :roll:

asmi
Forum Hero

Topics: 1043
Posts: 4,609

03/15/04 - 12:50 AM

its the same what jb00 or what i said ..its type 1 angiotensin II receptor blocker or AT-1 receptor blocker .

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