Acute hyponatremia

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Acute hyponatremia

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cirus
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08/20/07 - 12:52 AM

In case of acute Hyponatremia <24hrs (eg due to Oxytocin)

UW says if Na is <110 + symptomatic---> its no problem for rapid correction as the brain is not yet accomodated to this low level

Is this true or we should just stick to 0.5mEq/hr to avoid pontine myelinolysis??

Shaina
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08/20/07 - 02:38 AM

if pt has seizure,immed administer 3%saline irrespective of level of hyponatremia,

liliaeliz
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08/20/07 - 10:14 AM

only in chronic >72hs you can give slowly to prevent CPM

liliaeliz
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08/20/07 - 10:27 AM

Most patients with hyponatremia are asymptomatic and have a plasma sodium concentration above 120 meq/L. Initial treatment in such patients typically consists of gradual correction of the hyponatremia via water restriction or the administration of isotonic saline (or oral salt) [1]. More aggressive therapy is indicated in patients who have symptomatic or severe hyponatremia (plasma sodium concentration below 110 to 115 meq/L). In this setting, hypertonic saline can be given initially to raise the plasma sodium concentration, although the rate at which this occurs must be carefully monitored to minimize the risk of central demyelinating lesions

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