shroomysoup
Forum Newbie
Topics: 3
Posts: 3
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Sorry if my work is hard to read because it wouldn't let me format the way I wanted to. Please help! Thanks.
1) A starting pediatric dose of DILANTIN sodium is 6 mg/kg/day, administered in three equally divided doses. Using tablets containing 50 mg of phenytoin sodium, a pharmacist prepared a suspension such that each 1 mL, delivered from a calibrated dropper, contained a single dose for a 44 pound child. How many tablets should be used to prepare 30 mL of the suspension? (Answer is 24 tablets)
I did
6 mg x
------ = ---- with x = 120 mg
2.2 lbs 44 lbs
Then I did:
120 mg x
----------- = ---- with x = 3600 mg
1 mL 30 mL
Then I did:
3600 mg x 1 Tablet
---------- = 72 tablets (wrong of course)
50 mg
2) How many mg each of REGLAN. ATIVAN, and COMPAZINE are contained in each mL of the injection? (Answers: REGLAN = 1.13, ATIVAN = 0.0075, COMPAZINE = 0.075)
REGLAN (5 mg/mL) 30 mL
ATIVAN (2 mg/mL) 0.5 mL
Mannitol, 25% 50 mL
COMPAZINE (5 mg/mL) 2 mL
Dextrose Injection, 5% 50 mL
(For REGLAN, I did:
5 mg x
------- = ----- with x = 150 mg
1 mL 30 mL
Then I did:
150 mg x
--------- = ------- with x = 3 mg (wrong answer)
50 mL 1 mL
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| drgho
Forum Junior
Topics: 1
Posts: 116
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for phenytoin, the dose is 6mg/kg/day but given as 3 divided doses amd each dose in 1ml of injection. so 1 ml must conains 6 mg * 20 kg /3 times a day = 40 mg which is 0.8 tablets. for 30ml, 0.8 * 30 = 24 tablets.
for the second question, total volume is 30ml + 0.5ml + 50ml +2ml + 50ml which is 132.5ml, not 50ml.
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