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Kaplan Qbank USMLE



Author4 Posts
  #1

A 35-year-old woman consults an ophthalmologist because of double vision and droopy eyelids. She also has complaints of generalized muscle weakness. IV injection of edrophonium dramatically, but only briefly, reverses her symptoms. This patient's probable disease has a pathophysiologic basis that is closest to that of which of the following conditions?

A. Bullous pemphigoid
B. Diabetes mellitus type 1 (some cases)
C. Idiopathic Addison disease
D. Insulin resistance
E. Systemic lupus erythematosus

Edited by new_n_lost on 09/03/07 - 01:35 PM. Reason: Ads Not Allowed in Posts

  #2

(D) DM II

I was shocked when i knew the ans to this qs, but I surched it out, apparently some of type II r thin pts & have antibodies competing with their insulin for insulin receptors thus creating type II DM


  #3

D

Insulin resistance: Antibodies to insulin receptors
Myasthenia gravis: Antibodies to acetylcholine receptors of neuromuscular junctions
Also Grave's disease: Antibodies to thyrotropin receptors

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  #4

D--both are type 2 hypersensitivity reactions.

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