Prep for USMLEPrep for USMLE Forum
   Forum    Step 1  Step 2 CK Step 2 CS Step 3  Match  IMGs Resources Search






Previous Topic | Next Topic  wobble hypothesis 




 
Kaplan Qbank USMLE



Author4 Posts
  #1

what does it explains ?

  #2

accurate base pairing is req only in 1st 2 nucleotides of mRNA codon, so codons differing in the 3rd wobble position may code for the same tRNA /AA.
it's like a SILENT mutation

  #3

and it explains that genetic code is degenerate

  #4

Isn't the wobble hypotheses that the third position of the codon on the mRNA and the first position of the anticodon on the tRNA are bound less tightly(hence the wobble) than the other 2 base pairs, allowing a single tRNA to translate several different codons for the same amino acid?

It accounts for the degeneracy of the genetic code and also allows unusual base pairing to occur.







You don't have permission to post.




Login or Register to post messages in this topic





















Contact | Leaders | Disclaimer | Privacy

Copyright @ Prep for USMLE. All rights reserved.