new_n_lost
Politically InCorrect
Topics: 654
Posts: 6,112
|
In a Sense u r right. the Exact Mech is that Thiazides hinder the NaCl tranpsort in the DCT which leads to Sodium loss in the urine which has a result of INCREASED Na and Water Reabsorption in the Proximal Tubules. thus leading to dec load of Salt and Water to the Effected area to upon. Nephrogenic DI is characterised by ADH resistence i.e there is little effect of ADH, thus if u dec the load presented the deficit is relatively small and can be easily overcome by whtever little effect of ADH remains.
___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
|
|
| |
| |
