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Kaplan Qbank USMLE



Author7 Posts
  #1

This is a question from Kaplan notes...there explaination explains the answer but i have doubt abt one more choice...

Which of the following would tesnd to reduce the wall tension in an aneurysym in the lower abdominal aorta?

A) Light Exercise
B)Maintaining Supine position
C) A beta agonist
D) An alpha agonist

Edited by hope4dabest on 08/11/07 - 10:17 PM

  #2

D

  #3

why d?

  #4

shaking headshaking head

  #5

Answer is B
Explaination---there r 2 factors that affect wall tension: the radius of the vessel and pressure as T is directly prop to P and r. The wall tension of an aneurysym is greater than the surrounding vessel because it has greater radius. The larger the aneurysym, the greater the wall tension. Vessel pressure also raises wall tension directly and possibly indirectly by causing an increase in radius. Of the choices given only maintaining a supine position would reduce wall tension. In an upright position the effect of gravity increases pressure in vessels below heart level. A supine posture elimitaes this gravity effect. None of the other choices would reduce pressure in abd aorta, rather they would likely incrrease pressure and wall tension.......


now i have a confusin that y r they stressing on pressure...alpha agonist can constrict the vessel and can decrease the wall tension....y not this way??

  #6

Well, you expect an alpha agonist to constrict the aorta!! shaking headThis can't be, stimulation of alpha receptors can't constrict the aorta or any of the large arteries because of two reasons:
1.Functionally, constricting them will lead to a very high increase in work load on the heart eventually leading to heart failure, so they normally act as low resistance expandable vessels that convert bl.flow to pulsatile.
2.Anatomically, the walls of these vessels consist almost from elastic fibers with very few smooth muscle fibers so they can't constrict, conversely the elastic fibers enable them to serve the aforementioned function.
So administrating an alpha agonist will only lead to arteriolar constriction with increase in TPR which will elevate Bl.pressure (especially diastolic in aorta) and lead to an increase in wall tension.

Hope I explained it right.
GL
nod

  #7

Well thanks a lot...i had no idea of this..







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