gr_calif
Forum Junior
Topics: 3
Posts: 51
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NO! i think they r different.
I CELLS as u have mentioned is a part of the enteric endocrine system, :arrow: present in the upper intestine/duodenum, and is responsible for secretion of CCK.just like S CELLS secrete SECRETIN and G CELLS secrete GASTRIN.
I CELL DISEASE is an inherited lysosomal storage disorder . One unique feature of this disease when first described was the presence of phase-dense intracytoplasmic inclusions in the fibroblasts of patients. These cells were termed inclusion cells, or I-cells; thus, the disease was designated I-cell disease :arrow: These are observed in cells of mesenchymal origin, especially fibroblasts.
i hope its a convincing explanation :roll:
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| crista
Forum Guru
Topics: 121
Posts: 408
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thank you for your answer;it's something new for me.
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| gr_calif
Forum Junior
Topics: 3
Posts: 51
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MEANT U AGREE OR DISAGREE? :roll:
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| crista
Forum Guru
Topics: 121
Posts: 408
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seems to be logical that "I" is from inclusion (that was new...)
I agree  with you
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| rida
Forum Guru
Topics: 109
Posts: 721
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An extra addition to I cell disease is also that its due to failure of addition of mannose 6 phospate to lysosome proteins, causing these enzymes to be secreted out the cell instaed of being targeted to lysosome.
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