keepgoing
Forum Fanatic
Topics: 115
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its c,b/c it is not metabolised in liver so DOC in alcholics,liver transplant or any other liver pathology!!
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| simi
Forum Elite
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yes KG rt ..in the explanation given..lorazepam undergoes extrahepatic conjugation n is safer in terms of possibility of excessive CNS depression...is there any concept about how extrahepatic metabolism causes less CNS depression
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| new_n_lost
Forum Hero
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c)conjugated extrahepatically
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| po
Forum Elite
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it does not have active metabolites as other benzo's and is less lipophilic so doesnt get into cns like others.
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| simi
Forum Elite
Topics: 53
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thanks a lot po..that explanation helped me a lot
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