krsma
Forum Elite
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Endonuclease activation and chromatin fragmentation are characteristic features of eukaryotic cell death by apoptosis. Which of the folowing hcromosome structures would most likely be degraded first in an apoptotic cell?
A. barr body
B. 10 nm fiber
C. 30 nm fiber
D. Centromere
E. heterochromation
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| Bela
Forum Guru
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Posts: 412
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B) 10 nm fiber ????
I say this b/c DNA is unprotected, unlike in the solenoid shape of 30nm but could be wrong.
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La vita e bella!
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| usmleasr
Forum Guru
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Posts: 970
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i also think so 10 nm fiber
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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yep 10 nm fiber ( without H1 is the most open structure to be attacked first)
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| krsma
Forum Elite
Topics: 40
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Yes, all of you are right
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| Malaysian
Forum Guru
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I thought the structure held by H1 is known as 30nm fibers.......shouldn't the answer then be 30nm???
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| Malaysian
Forum Guru
Topics: 28
Posts: 778
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Ok I got it....the Q says endonucleases....if it was exonuclease then it would have been 30nm right??
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| krishie
Forum Senior
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Isnt the 10nm fibre the most open structure listed?The exonuclease must also degrade 10nm,right?Please clarify me.Thanx
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krish
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