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Kaplan Qbank USMLE



Author4 Posts
  #1

what are some of the functions of Peroxisomes?

there are atlease 4 but try your best.

  #2

Peroxisomes are organelles that contain oxidative enzymes,
some of its functions are:
Breakdown (by oxidation) of excess fatty acids.
Breakdown of hydrogen peroxide (H2O2), a potentially dangerous product of fatty-acid oxidation.
Paicipates in the synthesis of cholesterol.
Participates in the synthesis of bile acids.
Participates in the synthesis of the lipids used to make myelin.
Breakdown of excess purines (AMP, GMP) to uric acid

:idea: i guess its also important to know the disorders associated with peroxisomes....can u name them?

  #3

1. cerebrohepatorenal syndrome(zellweger)
2.neonatal adrenoleukodystrophy
3.infantile refsum disease
4.hyperpipecolatemia.....what is it, any idea :roll:

  #4

A metabolic disorder in which serum concentrations of pipecolic acid are greatly increased; characterised by hepatomegaly and progressive, generalised demyelination of the nervous system .
Pipecolic acid is an intermediate in lysine catabolism. most patients with hyperpipecolatemia are part of the Zellweger-neonatal adrenoleukodystrophy-infantile Refsum continuum--- :shock: this is what i could summarise from google search! sounds too much for us!!!! :?







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