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Kaplan Qbank USMLE



Author6 Posts
  #1

A)Which one corresponds to 10 nm and 30 nm size.,which one is sensitive to nucleases and insensitive to nucleases .

1. euchromatin
2.heterochromatin

B) histone helps in packaging of nucleosome:

1.H2
2.H3
3.H1
4.H4

C) which one relaxes + supercoils and which one relaxes negative supercoils.
1. topoisomerase I
2. DNA gyrase

  #2

H1 helps in packaging of nucleosomes.

  #3

:idea: Which one corresponds to 10 nm and 30 nm size, which one is sensitive to nucleases and insensitive to nucleases.

1. Euchromatin ---> 10nm sad sensitive to "Nucleases"
2. Heterochromatin --> 30nm


:idea: Histone helps in packaging of Nucleosome:
1.H2 *
2.H3 *
3.H1 -----> this is for tightening nucleosomes together
4.H4 *

:idea: Which one relaxes (+) supercoils and which one
relaxes (-) supercoils.

1. topoisomerase I ---> relax (-) supercoils
2. DNA gyrase or topoisomerase II ---> relax (+) supercoils

uhm...
:-k

___________________
Kris2c

  #4

sad i am not sure about super coils other two i agree with kris..H1 is linker DNA ..other 3 H2 H3 H4 form nucleo somes..
euchromatin is one expressed ..so has to be loosely bound...10nm fibers..
heterochromatin is condensed..30 nm fiber

  #5

Thanks kris,

You are absolutely right :icon_salut:


Heterochromatin is insensitive to nucleases .

  #6

what is + supercoil?
& what is - supercoil??







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