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Kaplan Qbank USMLE



Author12 Posts
  #1

A 35-year-old man is referred to the renal clinic for evaluation of proteinuria. He has no
complaints other than foamy urine. The following data are obtained from the patient:
Inulin clearance 100 mL/min
Plasma osmolarity 286 mOsm/L
Plasma sodium concentration 140 mEq/L
Urine flow 1.44 L / 24 hour
Urine osmolarity 205 mOsm/L
Urine sodium concentration 100 mEq/L
How much sodium does this patient reabsorb each day?
A. 14 mEq
B. 144 mEq
C. 244 mEq
D. 20,016 mEq
E. 20,160 mEq

  #2

Inulin clearance 100 mL/min-LOW
Inulin clearance Male:124 ± 26 ml/min
Female:119 ± 13 ml/min
REF-http://courses.washington.edu/hubio562/normalLabs.html
Plasma osmolarity 286 mOsm/L-NORMAL[N-276 - 295 mOsm/kg]
Plasma sodium concentration 140 mEq/L-NORMAL
Urine flow 1.44 L / 24 hour-7ml/6min-ie more than 1ml/min~NORMAL
Urine osmolarity 205 mOsm/L-IS LESS THAN PLASMA-ABNORMAL
Urine sodium concentration -?

cant get anywhere with this Q,shaking head

  #3

got some links that gives formula applied that got ZERO AS ANSWER.

http://www.life.umd.edu/classroom/bsci440/higgins...
http://sprojects.mmi.mcgill.ca/nephrology/present...
I would like to get this concept clear though mugging up is always llast option.grin

  #4

So many conversions to do before doing the actual work--just gotta love these types of q's nod

Is it A?


  #5

would really like to love the Q,only if I could understand it raised eyebrow

  #6

Is it the equation - [GFR X Px - Urine volume X urine conc. of the solute] ???
My answer ud be A using that equation for determining absorption vs. secretion.

Do u think they`d give us such big calculations anyways??? I mean ... it took me more than 72 seconds to convert the units rolling eyes but may I`m just dumb and there are easier ways to go around it raised eyebrow

___________________
When you reach the end of your rope, tie a knot in it and hang on!!

  #7

can anyone plzz explain how and what is the answer???

  #8

evn i was using the avove formula bu doesnt come to 14 i guess....here gfr gonna be 100 in this case...right???

  #9

Using the formula by kiterunner and after adjusting the units, I got D.

  #10

the answer is A

sodium reabsorbed =amount filtered - amount excreted

amount filtered =GFRXplasma Na conc

=100X140 or 0.1X140=14

rate of excretion=urine flow xurine Na conc

1.44l/24hr=1.44x100/24X60

=0.1

so Na reabsorbed =14-0.1=13.9 so 14 A is answer


  #11

13.9 mEq is the amount reabsorbed in 1 min. The question is for one day and it should be D.

  #12

It's D.







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