DrVirgo
Forum Hero
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What is the appropriate response of aldosterone...to postural changes -lying down to sitting up?
Normally when is aldosterone higher? Lying down or sitting up?
asking becasue if
appropriate response --> Hyperplasia --> Tr. not surgical
no/wrong response --> Adenoma --> Tr. Surgical
Thanks.
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| doc179
Forum Guru
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well I hope I got your qn correct. I think physiologically aldosterone level should be high once you go from a lying down position to a sitting up or standing up position. and hence its low when one is lying down.
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| Drtweetie
Forum Elite
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you're absolutely right, doc179
Normal response to prolonged standing-->activation RAA axis-->elevated aldosterone
check this out: http://www.pubmedcentral.nih.gov/articlerender.fc...
Great q for physio review, DrVirgo!
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| khorshid
Forum Guru
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also you can compare the aldosterone levels first thing in the morning and 4 hours later (8a.m and noon):
NL ppl and hyperplasia: increase
adenoma: decrease
or you can compare blood samples from adrenal veins: one sided increase: adenoma, both sides: hyperplasia
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