cirus
Forum Guru
Topics: 108
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38) A 55-year-old woman comes to the physician because of hot flashes. She first noted them about 9 months ago, and since then they have been worsening. She states that the flashes come on at various times throughout the day, but that they are especially intense at night. She had her last menstrual period approximately 5 months ago. Her medical history is significant for a pulmonary embolus at the age of 36 and severe depression. She takes fluoxetine for depression and has no allergies to medications but smokes one pack of cigarettes per day. Physical examination is unremarkable, including a normal pelvic examination. Which of the following is the most appropriate pharmacotherapy for this patient?
A. Clonidine
B. Estrogen and progesterone
C. Estrogen only
D. Glucophage
E. Tamoxifen
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| neuroblastoma
Forum Guru
Topics: 109
Posts: 1,091
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B EATROGEN+PROGESTERONE???
TMOXIFEN side effect-hot flashes
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| cirus
Forum Guru
Topics: 108
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ur ans is absolutely CI as she has hist of DVT ( always look DVT hist with est, they love it)
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| Justice
Just signed contract
Topics: 118
Posts: 2,372
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I know that Clonidine can alleviate flashes, but it is not approved by FDA for this purpose... Can balanced Est+Prog be indicated in a woman with this PMH?
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| neuroblastoma
Forum Guru
Topics: 109
Posts: 1,091
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yes,u are rightttttt
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| cirus
Forum Guru
Topics: 108
Posts: 740
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the ans is Clonidine..
I never knew about this drug untill yest
It is an absolute CI to use est, or balanced est or progest with DVT hist..
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| kpmle2
Forum Guru
Topics: 95
Posts: 512
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good Q
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