new_n_lost
Forum Hero
Topics: 724
Posts: 6,396
|
Had TO Search this
"Prevents uptake of lithium by epithelial cells. Has less potential for lithium toxicity because has a weak natriuretic effect and is less likely to increase lithium level by causing volume contraction. Has the advantage of being potassium-sparing; hypokalemia itself may potentiate a defect in concentrating ability. Also induces less extracellular fluid contraction than thiazides." Emedicine
___________________
"never argue with a fool, they'll bring you down to their level and beat you with experience" FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
|
| paheli
It'sAllAboutGoodKarma
Topics: 197
Posts: 2,720
|
ok, here's what i understood:
basically, you want to get rid of the Li. if any other diuretic is used, it will work in proximal part of nephron. this will allow reabs of Li in distal part[this is becoz Li is an ion similar to Na] so, using a diuretic that works in distal part of tubule, such as amiloride, prevents its reabs, and hence encourages its excretion.
hope this helps.
p.s. by the same logic, something like triamterene should also work, but amiloride is the preferred one.[but i'll admit i don't know why]
___________________
Prepare as if you're the worst, Perform as if you're the best! As you dream, so you manifest. So, DREAM BIG!! When you face hardship, remember, God never gives you more than you can handle. Keep your face to the sunshine and you cannot see the shadows. Internship, Here I come!!
|
| simi
Forum Elite
Topics: 53
Posts: 361
|
NNL n paheli..thanks alot...just now did some reading on this topic!
|
| Ig F
Forum Elite
Topics: 3
Posts: 440
|
 i got tht
___________________
i m not perfect but i wanna get close to it......
|
|
| |
| | | | |
Similar forum topics