new_n_lost
Politically InCorrect
Topics: 650
Posts: 6,058
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b-----chloramphenicol = 70S
A-----tetracycline - 30S
C-----rifamycin = DNA dependent RNA Polymerase Inhibitor
D-----erythromycin = 50S
E-----actiomycin D = DNA dependent RNA Synthesis.
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| dallas22
Forum Newbie
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Thanks.....
GL
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| dr ruman
Forum Elite
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Posts: 412
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i believe its Erythromycin
tetracyclines inhibit Elongation by inhibiting binding of aminoacyl tRna to ribosome
aminoglycoside inhibit Initiation by binding to 30s
erythromycin inhibit TRANSLOCATION by binding to peptidyl trna on 70 s
Chlorampgenicol inhibit PEPITDYL TRANFERASE ENZYME part of large subunit 50s ,so chloramphenicol doesnt bind to 70s,rther inhibit translocation by binding to enzme in 50 s
cholaramphenicol inhibt PEPTIDYL transferase biniding 70s
rifampin inhibit RHO factor and hence prokaryotic Rna polymerase
actinomycin inhibit both eukaryotic and prokaryotic
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| dr ruman
Forum Elite
Topics: 29
Posts: 412
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i believe its Erythromycin
tetracyclines inhibit Elongation by inhibiting binding of aminoacyl tRna to ribosome
aminoglycoside inhibit Initiation by binding to 30s
erythromycin inhibit TRANSLOCATION by binding to peptidyl trna on 70 s
Chlorampgenicol inhibit PEPITDYL TRANFERASE ENZYME part of large subunit 50s ,so chloramphenicol doesnt bind to 70s,rther inhibit translocation by binding to enzme in 50 s
NOTE PLEASE CORRECTION ,THE LINE ADDED MISTAKELY(cholaramphenicol inhibt PEPTIDYL transferase biniding 70s) THIS IS WRONG
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Living each day as a preparation for the next is an exciting way to live. Looking forward to something is much more fun than looking back at something—so lets do it together
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| silver
Forum Guru
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Posts: 771
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D-----erythromycin
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| new_n_lost
Politically InCorrect
Topics: 650
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Yes U R Right Dr. Ruman i made An Essential Mistake. Didnt read teh Question Properly and i sincerely hope that i dont do the same in the Exm.
Chlorophenicol Indirectly INHIBITS the TARANSPEPTIDATION by Blocking Amioncayl moiety of Charged tRNA molecule on the mRNA complex which is a 70S Complex.
Macrolides and Clindamycin Act via the INHIBITION OF TRANSLOCATION OF THE PEPTIDYL tRNA on the 50S subunit of the mRNA complex.
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| Kalyann
Forum Elite
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its a kaplan lecture notes q....
i also stumbled on it.
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| macintosh
Forum Elite
Topics: 38
Posts: 178
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I still do not understand your point. Whats with the 50s and the 70s?
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